The Rebel Podcast

Ep. 84 – Live in Harmony With Your Nature: 8 Predictive Biomarkers For Lifetime Health – with Dr. Russell Jaffe

Dr. Russell Jaffe returns to discuss the eight predictive biomarkers for lifetime health! Dr. Jaffe is considered one of the pioneers of integrative and regenerative medicine, continually seeking new ways to help speed the transition from our current healthcare system’s symptom reactive model to a more functionally integrated, effective, and compassionate system.

And understanding what these eight tests are and what they indicate is a critical step in that transition because it empowers you, as an individual, with the knowledge necessary to advocate for your own health — not for treatment after you’re sick, but for preventative treatment that helps you maintain optimal health.

So, why these eight tests? 

That’s because 92% of your lifetime health outcomes are the result of lifestyle habits (or epigenetics), and these eight functional tests will provide the most comprehensive measure of whether your lifestyle habits are contributing negatively or positively to your health. More than that, referencing where your results fall near the optimal results range for each test can give you and your healthcare provider the information necessary to make specific lifestyle changes that will have the greatest impact on your individual health.

The 8 Tests:

  • Test #1 = Insulin, blood sugar, carbohydrate metabolism = Hemoglobin A1C – measures extra sugar in our body.
  • Test #2 = (High Sensitivity) C-Reactive Protein: all-cause morbidity indicator.
  • Test #3 = Homocysteine or HCy: Methylation, repair of blood vessels and cardiovascular health
  • Test #4 = Lymphocyte & Immune Tolerance (Dr. Jaffe helped develop this one) – what environmental compounds can you tolerate without stressing digestion, sleep, mood, cognition, and performance?
  • Test #5 = The pH of our first morning urination: Measuring mineral status and cellular metabolic acidosis – the batteries inside the cell for cellular energy
  • Test #6 = Vitamin D (25-HydroxyD): how this “neurohormone” functions in cellular cross-talk and plays a major role in mitigating cellular mutations (Cancer)
  • Test #7 = Omega 3 index – The Omega-3:Omega-6 Ratio
  • Test #8 = 8-Oxo-Guanine, Oxidative Damage from environmental toxins: How 8-Oxo-Guanine measures exposure to the VOC’s, POPs (hormone disruptors), mold, radiation, chemicals, pesticides, and other landmines from the 21st century! 

We break down the optimal values of each test in the episode, but you can also find a more detailed breakdown of what each test is measuring in this journal article: “Predictive Biomarkers in Personalized Laboratory Diagnosis and Evidence Based Best Practices Outcome Monitoring.”

If you need some assistance figuring out how to get the tests, what to say to your PCP, or interpreting the tests, I’d love to help you! You can book a free 20-minute consultation and we’ll talk about what’s best for you from there.

Finally, I want to leave you with Dr. Jaffe’s top tip for living optimally: “Live in harmony with your nature.”

Of course, that requires that you know your nature first! If you can discover your nature and live in harmony with that, THAT is the secret to happiness. Otherwise, it is going to fight with you.

Download this Episode MP3.


Do you want more to empower yourself through healthy living? Is your busy lifestyle an obstacle to your health? Join The Rebel Health Coach community for the support and knowledge you need for better performance, better business and a better you!

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Disclaimer: The activities and research discussed in these podcasts are suggestions only and are only advised to be undertaken following prior consultation with a health or medical professional. Fitness training, nutrition, and other physical pursuits should be tailored to the individual based upon an assessment of their personal needs.

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